Importance of national plans for Alzheimer’s disease and dementia

Bibliography of References to National Dementia Plans

Orbitofrontal Dysfunction Discriminates Behavioral Variant Frontotemporal Dementia from Alzheimers Disease

Background: Behavioral variant frontotemporal dementia (bvFTD) patients show prefrontal cortex dysfunction and atrophy. Methods: We investigated whether executive function in conjunction with prefrontal cortex atrophy discriminates bvFTD and Alzheimer’s disease (AD) patients efficiently at presentation. Results: AD and bvFTD patients were distinguishable by 89.5% on their performance of 3 execu...

The importance of helplines in National Plans

In the last years, the Internet has attracted a considerable attention as a means to provide health-related information. Rare diseases patients have been described as active internet users, accessing the web both for searching activities and for communication purposes [1]. Despite the great opportunities offered both by health 1.0 and health 2.0 applications, some concerns arise as well, partic...

Automatic Classification of Alzheimers Disease vs. Frontotemporal Dementia: A Decision Tree Approach with FDG-PET

We introduce a novel approach for the automatic classification of FDG-PET scans of subjects with Alzheimers Disease (AD) and Frontotemporal dementia (FTD). Unlike previous work in the literature which focuses on principal component analysis and predefined regions of interest, we propose the use of decision tree learning combined with empirically determined regions of interest as attributes. The...

Magnesium and Alzheimers Disease: The Cholinergic Hypothesis

The cholinergic deficit in Alzheimer’s disease (AD) remains the cornerstone for the understanding of chemical signal transfer. Hypofunctions of cholinergic systems are significantly involved in the signs and symptoms of senile dementia of the Alzheimer type. Cognitive deficits in AD have been widely associated with dysfunction of the cholinergic system. As a diagnostic marker of AD the activity...